Anticonvulsant and free radical scavenging activity of Hybanthus enneaspermus: A preliminary screening
نویسندگان
چکیده
Anticonvulsant activity of aqueous (AQHE) and ethanolic (ETHE) extract of Hybanthus enneaspermus was studied using maximal electric shock (MES) and strychnine induced convulsions models. AQHE at the doses of 200 mg/kg and 400 mg/kg orally showed significant protection in both models. The activity was equipotent to phenobarbitone sodium (30 mg/kg; i.p.). The AQHE showed no neurotoxicity. Ethanolic extract did not show protection in these models. The AQHE exhibited free radical scavenging activity in an in vitro system using DPPH.
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